Health is on everyone’s mind at the moment, but we often find ourselves lost, with the evergrowing pharmaceutical market, what is good and what just isn’t? We often rely on pretty packaging or commercials that trick us into getting a product that might not even be good for us in the first place. That’s why it’s important to do our research and consider everything. Treating any disease or syndrome is a tricky process that needs extra care and knowledge. Reading labels might seem boring, every supplement is the same and does the job, right? Wrong, the can differ quite a bit and it’s on you to be careful! Here are some things to look out for when getting supplements for MTHFR!

What is MTHFR?

Methylenetetrahydrofolate reductase or more commonly known as MTHFR is a gene. We have two copies of this MTHFR gene, and through them, we create an enzyme that helps break the amino acid homocysteine down. Now, like anything, this gene can vary from person to person so it’s likely that some people may get a different variant and that little difference can cause damage to the body itself. When these types of mutations of the gene occur, they can lead to all sorts and kinds of difficulties like processing amino acids that can, later on, cause problems. That’s why it’s important to get diagnosed on time and start treating the issue right away, as this can make a big difference in someone’s life. Also, this means that the treatment itself can and will differ depending on what kind of mutation you have!


Health should be a top priority to anyone, and this means looking after your diet and what you put inside your body as well! A lot of things simply can’t be fixed with a good diet, as experts at state, the key to keeping your health in tip condition is by consuming the right vitamins and supplements your body needs. Adding a proper dosage of L-Methylfolate to your daily routine and nutrition can make a difference. But as with most things, it all depends on how your body reacts, some people need to add more additional vitamins and nutrients to go with the methylfolate supplement and some don’t. It’s always going to differ from person to person, so choose your supplements wisely, depending on your needs.

B12 vitamins

People who suffer from MTHFR need to be careful when searching for the right supplement to treat their symptoms, most people with an MTHFR gene mutation have trouble breaking down folic acid and using it properly the way the body needs to. But it all depends on the type of the MTHFR variant, the number of mutations, and other factors that may determine if taking B12 is good or not.

But one of the common forms of active B12 is hydroxocobalamin, but you should always do your research and ask your doctor for your specific gene mutation in order to find the best solution for you. What works good for other people, might not work well for you, that’s why it’s important to do as much research as you can!


This is probably one of the key components that should be consumed to achieve the best results. Magnesium acts as a good co-factor that a lot of people might be lacking in, so it’s important to be consumed as much as any vitamin and nutrient. Ask your doctor about consuming this, like with everything else, make sure you can safely use this supplement beforehand.

Avoid supplements with fillers and dyes

Not many people pay attention to what is really inside of supplements, why would they, all medication is good…but is it tho? Only a small percentage of people read the sometimes lengthy list of ingredients at the back of the bottle and many times they would just look past the other ingredients that aren’t listed on the label. Some of these supplements contain harmful ingredients like fillers or dyes. They are often made from substances that are not so good for the body, and should be avoided!

Ask a professional

At the end of the day, the safest way to find out what you actually need to treat a specific syndrome or in this case an MTHFR gene mutation is simply asking a professional. Talking to your doctor and determining the exact type of mutation will help you greatly in your search for the right supplement that will help battle all the symptoms caused by the mutation itself. Do your research, go to your doctor, it’s always better to be safe than sorry!